Tóm tắt

The Nobel Prize in Physiology or Medicine signifies that cancer immunotherapy is becoming the most promising direction in cancer research. In this paper, we review the different mechanisms of the human immune system in inhibiting cancer grow and the possible loopholes allowing the cancer cell to evade the immune system response. Understanding these mechanisms allows designing many different strategies to treat cancer using the patient’s immune system as the major ‘fighting force’. We would also review the most recent clinical trials in cancer immunotherapy and briefly explain the remaining challenges on applying cancer immunotherapy in larger scale. * Key words: Cancer immunotherapy.

Abstract

The Nobel Prize in Physiology or Medicine signifies that cancer immunotherapy is becoming the most promising direction in cancer research. In this paper, we review the different mechanisms of the human immune system in inhibiting cancer grow and the possible loopholes allowing the cancer cell to evade the immune system response. Understanding these mechanisms allows designing many different strategies to treat cancer using the patient’s immune system as the major ‘fighting force’. We would also review the most recent clinical trials in cancer immunotherapy and briefly explain the remaining challenges on applying cancer immunotherapy in larger scale. * Key words: Cancer immunotherapy.