Tóm tắt

Objectives: To investigate the glomerular filtration rate (GFR) and urine osmolality (UOsm) and their relationship with general characteristics of patients with ureteral stones at E Hospital. Subjects and methods: A cross-sectional study on 183 patients with ureteral stones who were indicated with laser retrograde lithotripsy. All patients were calculated GFR, collected a 24-hour UOsm. Results: The average GFR was 68.91 mL/minute, 31.7% of patients had GFR < 60 mL/minute. The average osmolality was 468 mOsm, a decreasing UOsm was observed in 87.4%. UOsm was positivelly correlated with GFR at moderate level (r = 0.256, p < 0.05). Average GFR, UOsm was lower than non-hypertension and non-diabetic group. Rate of patients with GFR < 60 mL/min and reducing UOsm was higher significantly compared to the group of non-hypertension and non-diabetes (p < 0.05). GFR and UOsm gradually reduced by the severity of pelvic dilatation (p < 0.01). Conclusions: Reduced GFR, low UOsm are common and positively associated with the severity of pelvic dilatation in ureteral stones patients who were indicated laser retrograde lithotripsy. * Keywords: Ureteral stones; Laser retrograde lithotripsy; Glomerular filtration rate; Urine osmolality.

Abstract

Objectives: To investigate the glomerular filtration rate (GFR) and urine osmolality (UOsm) and their relationship with general characteristics of patients with ureteral stones at E Hospital. Subjects and methods: A cross-sectional study on 183 patients with ureteral stones who were indicated with laser retrograde lithotripsy. All patients were calculated GFR, collected a 24-hour UOsm. Results: The average GFR was 68.91 mL/minute, 31.7% of patients had GFR < 60 mL/minute. The average osmolality was 468 mOsm, a decreasing UOsm was observed in 87.4%. UOsm was positivelly correlated with GFR at moderate level (r = 0.256, p < 0.05). Average GFR, UOsm was lower than non-hypertension and non-diabetic group. Rate of patients with GFR < 60 mL/min and reducing UOsm was higher significantly compared to the group of non-hypertension and non-diabetes (p < 0.05). GFR and UOsm gradually reduced by the severity of pelvic dilatation (p < 0.01). Conclusions: Reduced GFR, low UOsm are common and positively associated with the severity of pelvic dilatation in ureteral stones patients who were indicated laser retrograde lithotripsy. * Keywords: Ureteral stones; Laser retrograde lithotripsy; Glomerular filtration rate; Urine osmolality.