Tóm tắt

Objectives: To investigate some relationship between clinical features and breast cancer molecular subtypes. Subjects and methods: A retrospective, cross-sectional study on 495 breast cancer patients who were classified as subtypes by immunohistochemistry (IHC) stain. Results: 100% of TNB- belongs to younger group. LUMA is the most common at stage 1 (39.4%). TNB- and TNB+ at high risk accounted for the highest rate (50.0 and 43.5%). Conclusion: TNB-, TNB+ and HER2 subtypes are often associated in worse clinical factors than others, such as younger, higher risk category and advanced TNM stage. * Keywords: Breast cancer; Clinical features; Molecular subtype.

Abstract

Objectives: To investigate some relationship between clinical features and breast cancer molecular subtypes. Subjects and methods: A retrospective, cross-sectional study on 495 breast cancer patients who were classified as subtypes by immunohistochemistry (IHC) stain. Results: 100% of TNB- belongs to younger group. LUMA is the most common at stage 1 (39.4%). TNB- and TNB+ at high risk accounted for the highest rate (50.0 and 43.5%). Conclusion: TNB-, TNB+ and HER2 subtypes are often associated in worse clinical factors than others, such as younger, higher risk category and advanced TNM stage. * Keywords: Breast cancer; Clinical features; Molecular subtype.