TẠP CHÍ SỐ 7-TV NĂM 2016

Investigation of plasma amyloid beta 1-42 levels and its correlation with some cardiovascular risk factors in people over forty years old

Nguyen Van Hoan; Nguyen Thanh Binh; Doan Van De; Nguyen Linh Toan

Tóm tắt

Objectives: Amyloid beta 1-42 (Aβ 1-42) is related to several disorders including nervous, cardiovascular and metabolic disorder. We investigated plasma Aβ 1-42 level and examined its correlation with some cardiovascular risk factors. Subjects and methods: Level of Aβ 1-42 was measured in plasma of 40 people over forty years old without type 2 diabetes mellitus and hypertension by ELISA method. Results and conclusions: Average plasma Aβ 1-42 level was 98.88 ± 92.45 pg/mL, median was 65.49 pg/mL with wide range from 45.83 to 494.32 pg/mL. There was no significant correlation between plasma Aβ 1-42 level and cardiovascular risk factors such as age, plasma lipids. * Key words: Metabolic disorder; Amyloid beta.

Abstract

Objectives: Amyloid beta 1-42 (Aβ 1-42) is related to several disorders including nervous, cardiovascular and metabolic disorder. We investigated plasma Aβ 1-42 level and examined its correlation with some cardiovascular risk factors. Subjects and methods: Level of Aβ 1-42 was measured in plasma of 40 people over forty years old without type 2 diabetes mellitus and hypertension by ELISA method. Results and conclusions: Average plasma Aβ 1-42 level was 98.88 ± 92.45 pg/mL, median was 65.49 pg/mL with wide range from 45.83 to 494.32 pg/mL. There was no significant correlation between plasma Aβ 1-42 level and cardiovascular risk factors such as age, plasma lipids. * Key words: Metabolic disorder; Amyloid beta.

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TẠP CHÍ Y DƯỢC HỌC QUÂN SỰ - PHIÊN BẢN ĐIỆN TỬ
Tòa soạn: Số 160 - Đường Phùng Hưng - Quận Hà Đông - Thành phố Hà Nội
Trưởng ban biên tập tạp chí Y - Dược học Quân sự: Thiếu tướng GS. TS. Hoàng Văn Lương - Phó Giám đốc Học viện Quân y
Giấy phép số 345/GP-BVHTT ngày 08 tháng 08 năm 2002 của Bộ Thông tin và Truyền thông.
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