Tóm tắt

Milk thistle (Silybum marianum) is the most well-researched plant in the treatment of liver diseases. Fruits of milk thistle contain flavonoids known for silymarin including silybin, silydianin and silychristin. Although Silymarin has the most potent flavonoids in milk thistle, similar to other flavonoids, it is not well-absorbed. In recent studies, the phytosome technology has increased absorption of conventional herbal extract. This paper aims to review the researches about milk thistle phytosome including: manufacturing, bioavailability, safety and clinical efficacy. * Key words: Phytosome; Silybin; Bioavailability; Phosphatidylcholine.

Abstract

Milk thistle (Silybum marianum) is the most well-researched plant in the treatment of liver diseases. Fruits of milk thistle contain flavonoids known for silymarin including silybin, silydianin and silychristin. Although Silymarin has the most potent flavonoids in milk thistle, similar to other flavonoids, it is not well-absorbed. In recent studies, the phytosome technology has increased absorption of conventional herbal extract. This paper aims to review the researches about milk thistle phytosome including: manufacturing, bioavailability, safety and clinical efficacy. * Key words: Phytosome; Silybin; Bioavailability; Phosphatidylcholine.