Tóm tắt

Objectives: To determine the distribution and genetic diversity of A. baumannii strains isolated from inpatients at Thanh Nhan Hospital from 10/2017 to 10/2018. Subjects and methods: A descriptive study and laboratory analysis on sixty-seven A. baumannii strains from isolated samples of inpatient at Thanh Nhan Hospital from 2017 to 2018. Results: The distribution of A. baumannii strain in A. baumannii infected male was higher than in female, 89.5% of the patients were over 50 years of age. The rate of A. baumannii was highest with 61% (41/67) that isolated from sputum samples. Patients infected with A. baumannii in intensive care unit was 91%. Analyzing the genetic relationship of 67 strains of A. baumannii at Thanh Nhan Hospital with 12 RAPD primers obtained 126 DNA segments showed that each allele on the primer ranged from 7 - 19 alleles, 100% of the primers were for segment polymorphism. The obtained PIC coefficients ranged from 0.770 to 0.945; the average PIC value was 0.831; 67 strains were divided into 5 main groups, with genetic similarity coefficients ranging from 0.62 to 0.97, indicating that the 67 strains had a relatively large genetic diversity. Conclusions: These strains can be spread through numerous pathways, especially through contact transmission. Therefore, standard precautions and compliance with hospital infection control measures are essential. * Keywords: A. baumannii strain; Capital technique.

Abstract

Objectives: To determine the distribution and genetic diversity of A. baumannii strains isolated from inpatients at Thanh Nhan Hospital from 10/2017 to 10/2018. Subjects and methods: A descriptive study and laboratory analysis on sixty-seven A. baumannii strains from isolated samples of inpatient at Thanh Nhan Hospital from 2017 to 2018. Results: The distribution of A. baumannii strain in A. baumannii infected male was higher than in female, 89.5% of the patients were over 50 years of age. The rate of A. baumannii was highest with 61% (41/67) that isolated from sputum samples. Patients infected with A. baumannii in intensive care unit was 91%. Analyzing the genetic relationship of 67 strains of A. baumannii at Thanh Nhan Hospital with 12 RAPD primers obtained 126 DNA segments showed that each allele on the primer ranged from 7 - 19 alleles, 100% of the primers were for segment polymorphism. The obtained PIC coefficients ranged from 0.770 to 0.945; the average PIC value was 0.831; 67 strains were divided into 5 main groups, with genetic similarity coefficients ranging from 0.62 to 0.97, indicating that the 67 strains had a relatively large genetic diversity. Conclusions: These strains can be spread through numerous pathways, especially through contact transmission. Therefore, standard precautions and compliance with hospital infection control measures are essential. * Keywords: A. baumannii strain; Capital technique.