Tóm tắt

Objectives: To determine the level of antibiotic resistance to bacteria causing urinary tract infections (UTI) common at Military Hospital 103 in the period of 1/2017 - 12/2019. Materials and methods: The descriptive, mixed model (a combination of retrospective and prospective study) was conducted in all hospitalized patients at Military Hospital 103 from 01/2017 - 12/2019. Urine samples were collected by standard procedures. Tests were performed at the Department of Microbiology, Military Hospital 103, using the VITEK2 system (Bio Merieux). Results: The group of Gram-negative bacteria causing UTI with the level of ≥ 105 CFU/mL (61.2%) was higher than the group of Gram-positive bacteria (38.8%). The leading causes of UTI were E. coli (38.8%), Pseudomonas spp (13.2%), and Enterococcus spp (12.6%). E. coli was particularly resistant to ampicillin (92.3%) and trimethroprim/sulfamethoxazole (77.1%) but still highly sensitive to carbapenem antibiotics (82.5 - 85.7%). P. aeruginosa was highly resistant to the quinolone antibiotic group (84.2 - 84.6%) and only susceptible to colistin (91.9%). Except for vancomycin, which was less resistant to Enterococcus spp, the remaining antibiotics were highly resistant: Tetracycline (94.7%), erythromycin (92.5%). Conclusion: The number of bacteria is mainly isolated at ≥ 105 CFU/mL, in which the common strains are E. coli, Pseudomonas spp, and Enterococcus spp. Despite their resistance to many antibiotics, these strains remain highly susceptible to carbapenem, colistin, and vancomycin groups of antibiotics. The current situation of antibiotic resistance among bacteria causing UTI and using appropriate antibiotics are still a matter of strict control. * Keywords: Urinary tract infections; Antibiotic resistance.

Abstract

Objectives: To determine the level of antibiotic resistance to bacteria causing urinary tract infections (UTI) common at Military Hospital 103 in the period of 1/2017 - 12/2019. Materials and methods: The descriptive, mixed model (a combination of retrospective and prospective study) was conducted in all hospitalized patients at Military Hospital 103 from 01/2017 - 12/2019. Urine samples were collected by standard procedures. Tests were performed at the Department of Microbiology, Military Hospital 103, using the VITEK2 system (Bio Merieux). Results: The group of Gram-negative bacteria causing UTI with the level of ≥ 105 CFU/mL (61.2%) was higher than the group of Gram-positive bacteria (38.8%). The leading causes of UTI were E. coli (38.8%), Pseudomonas spp (13.2%), and Enterococcus spp (12.6%). E. coli was particularly resistant to ampicillin (92.3%) and trimethroprim/sulfamethoxazole (77.1%) but still highly sensitive to carbapenem antibiotics (82.5 - 85.7%). P. aeruginosa was highly resistant to the quinolone antibiotic group (84.2 - 84.6%) and only susceptible to colistin (91.9%). Except for vancomycin, which was less resistant to Enterococcus spp, the remaining antibiotics were highly resistant: Tetracycline (94.7%), erythromycin (92.5%). Conclusion: The number of bacteria is mainly isolated at ≥ 105 CFU/mL, in which the common strains are E. coli, Pseudomonas spp, and Enterococcus spp. Despite their resistance to many antibiotics, these strains remain highly susceptible to carbapenem, colistin, and vancomycin groups of antibiotics. The current situation of antibiotic resistance among bacteria causing UTI and using appropriate antibiotics are still a matter of strict control. * Keywords: Urinary tract infections; Antibiotic resistance.