Tóm tắt

Objectives: To describe the electrophysiological characteristics in type 2 diabetic mellitus patients treated at the National Hospital of Endocrinology. Subjects and method: A cross-sectional descriptive study 180 patients were diagnosed with type 2 diabetes according to the diabetes diagnostic criteria of the American Diabetes Association (ADA) (2015), being inpatient and outpatient treatment at National Hospital of Endocrinology. Results: 1. The results of motor conduction: The latency of the median nerve: 3.83 ± 0.69 ms, ulnar nerve: 2.61 ± 0.46 ms, tibial nerve: 4.25 ± 0.86 ms, peroneal nerve: 3.87 ± 0.87 ms. The velocity of the median nerve: 52.04 ± 5.16 m/s, ulnar nerve: 57.98.2 ± 6.55 m/s, tibial nerve: 42.65 ± 5.44 m/s, peroneal nerve: 44.73 ± 5.04 m/s. There was no difference amongst age groups, and gender (p > 0.05). The amplitude of the median nerve: 8.24 ± 2.24 µV, ulnar nerve: 7.38 ± 2.0 µV, tibial never: 10.63 ± 4.57 µV, peroneal nerve: 4.09 ± 2.71 µV. There was difference in latency of the tibial nerve, amplitude of the peroneal nerve and velocity of the ulnar nerve amongst different age groups (p < 0.05); 2. The result of sensory conduction: The latency of the median nerve: 2.85 ± 0.62 ms, ulnar nerve: 2.46 ± 1.32 ms, sural nerve: 3.03 ± 1.2 ms. The ampitude of the median nerve: 24.44 ± 10.12 µV, ulnar nerve: 24.1 ± 10.17 m/s, sural: 53.48 ± 8.09 m/s; tibial nerve: 47.78 ± 11.43 µV, peroneal nerve: 13.47 ± 4.85 µV. The amplitude range of the median nerve, ulnar nerve, sural nerve decreased with age group: The highest belonged to the age group < 40 years old, followed by the age groups of 40 - 49, 50 - 59. The group > 60 years of age had the lowest range (p < 0.05). There was no difference in the latency, amplitude of the conduction velocity of the median, tibial, ulnar, peroneal and sural nerves between men and women (p > 0.05). The motor conduction, amplitude of the median nerve, ulnar, tibial, peroneal of diabetes group decreased compared to the healthy group (p < 0.05), the latency of diabetic group increased statistically significantly (p < 0.05). The sensory conduction, amplitude of the median nerve, ulnar, sural of diabetic group decreased compared to the healthy group (p < 0.001), the latency of diabetic group increased with statistical significance (p < 0.05). Conclusion: The parameter of motor and sensory conduction (velocity, amplitude) in the group of type 2 diabetes patients decreased compared to the healthy group (p < 0.05); the latency of the diabetes group increased significantly (p < 0.05). * Keywords: Nerve conduction parameter; Type-2-diabetes; Perpheral neuropathy.

Abstract

Objectives: To describe the electrophysiological characteristics in type 2 diabetic mellitus patients treated at the National Hospital of Endocrinology. Subjects and method: A cross-sectional descriptive study 180 patients were diagnosed with type 2 diabetes according to the diabetes diagnostic criteria of the American Diabetes Association (ADA) (2015), being inpatient and outpatient treatment at National Hospital of Endocrinology. Results: 1. The results of motor conduction: The latency of the median nerve: 3.83 ± 0.69 ms, ulnar nerve: 2.61 ± 0.46 ms, tibial nerve: 4.25 ± 0.86 ms, peroneal nerve: 3.87 ± 0.87 ms. The velocity of the median nerve: 52.04 ± 5.16 m/s, ulnar nerve: 57.98.2 ± 6.55 m/s, tibial nerve: 42.65 ± 5.44 m/s, peroneal nerve: 44.73 ± 5.04 m/s. There was no difference amongst age groups, and gender (p > 0.05). The amplitude of the median nerve: 8.24 ± 2.24 µV, ulnar nerve: 7.38 ± 2.0 µV, tibial never: 10.63 ± 4.57 µV, peroneal nerve: 4.09 ± 2.71 µV. There was difference in latency of the tibial nerve, amplitude of the peroneal nerve and velocity of the ulnar nerve amongst different age groups (p < 0.05); 2. The result of sensory conduction: The latency of the median nerve: 2.85 ± 0.62 ms, ulnar nerve: 2.46 ± 1.32 ms, sural nerve: 3.03 ± 1.2 ms. The ampitude of the median nerve: 24.44 ± 10.12 µV, ulnar nerve: 24.1 ± 10.17 m/s, sural: 53.48 ± 8.09 m/s; tibial nerve: 47.78 ± 11.43 µV, peroneal nerve: 13.47 ± 4.85 µV. The amplitude range of the median nerve, ulnar nerve, sural nerve decreased with age group: The highest belonged to the age group < 40 years old, followed by the age groups of 40 - 49, 50 - 59. The group > 60 years of age had the lowest range (p < 0.05). There was no difference in the latency, amplitude of the conduction velocity of the median, tibial, ulnar, peroneal and sural nerves between men and women (p > 0.05). The motor conduction, amplitude of the median nerve, ulnar, tibial, peroneal of diabetes group decreased compared to the healthy group (p < 0.05), the latency of diabetic group increased statistically significantly (p < 0.05). The sensory conduction, amplitude of the median nerve, ulnar, sural of diabetic group decreased compared to the healthy group (p < 0.001), the latency of diabetic group increased with statistical significance (p < 0.05). Conclusion: The parameter of motor and sensory conduction (velocity, amplitude) in the group of type 2 diabetes patients decreased compared to the healthy group (p < 0.05); the latency of the diabetes group increased significantly (p < 0.05). * Keywords: Nerve conduction parameter; Type-2-diabetes; Perpheral neuropathy.