TẠP CHÍ SỐ 7-TA NĂM 2020

Concentrations of the serum resistin and visfatin levels in type 2 diabetic patients

Doan Viet Cuong, Hoang Trung Vinh, Ngo Thu Hang, Nguyen Linh Toan

Tóm tắt

Objectives: To investigate serum resistin and visfatin levels in patients with type 2 diabetes mellitus (T2DM). Subjects and methods: 391 subjects included 297 T2D patients and 134 nondiabetic people used as control. Serum resistin and visfatin levels were measured by EnzymeLinked Immuno Sorbent Assay (ELISA). Results: The concentrations of serum resistin and visfatin in patients with T2DM were significantly higher than those in non-diabetic people (p < 0.001). Serum insulin levels and HOMA-IR in diabetes groups were significantly higher than those in non-diabetic people. Conclusion: Serum resistin and visfatin levels were associated with type 2 diabetes patients and it may play important roles in pathophysiological mechanism of T2DM. * Keywords: Resistin; Visfatin; Type 2 diabetes mellitus.

Abstract

Objectives: To investigate serum resistin and visfatin levels in patients with type 2 diabetes mellitus (T2DM). Subjects and methods: 391 subjects included 297 T2D patients and 134 nondiabetic people used as control. Serum resistin and visfatin levels were measured by EnzymeLinked Immuno Sorbent Assay (ELISA). Results: The concentrations of serum resistin and visfatin in patients with T2DM were significantly higher than those in non-diabetic people (p < 0.001). Serum insulin levels and HOMA-IR in diabetes groups were significantly higher than those in non-diabetic people. Conclusion: Serum resistin and visfatin levels were associated with type 2 diabetes patients and it may play important roles in pathophysiological mechanism of T2DM. * Keywords: Resistin; Visfatin; Type 2 diabetes mellitus.

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